Arsene Wenger has made just one change to his side that lost 3-1 to Barcelona in midweek, with Francis Coquelin starting in place of the injured Mathieu Flamini, with Alex Iwobi keeping his place in the side.
David Ospina continues in goal in the absence of injured Petr Cech, with Nacho Monreal, Hector Bellerin, Laurent Koscielny and Gabriel in defence.
Francis Coquelin and Mohamed Elneny will be the Gunners central midfield partnership, with Mesut Ozil ahead in the No10 role.
Iwobi and Alexis Sanchez are selected on either wing with Danny Welbeck spearheading the attack. The likes of Olivier Giroud, Theo Walcott and Joel Campbell are named on the bench.
Arsenal’s twitter feed confirmed the lineups:
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— Arsenal FC (@Arsenal) March 19, 2016
Here is Everton’s lineup:
— Everton (@Everton) March 19, 2016